Antifungal Agents:


Fungi are microorganisms that include yeast and molds.


fungus-family-mold-diseades-illness.jpg


Yeast:
Molds:
Single celled
muticellurar
Reproduce by budding
long, branching filaments called hyphae


How do you get a fungal Infection? ……


1. Orally 2. Grow on your skin or nails 3. Inhaled



Four types of fungal Infections:
1. Cutaneous
2. Subcutaneous
3. Superficial
4. Systemic (Blood à whole body)


Examples:
1. athletes-foot-tinea-pedis.jpg 2.chromoblastomycosis5.jpg 3. 1890.jpg 4. nrn1032-f2.jpg





Quiz Time!!!

1. Which two are not Antifungal Drugs?


A. Amphotericin B
B. Fluconazole (Diflucan)
C. Primaquine
D. Ketoconazole
E. Nystatin
F. Pentamidine





2. What types of toxicities can Antifunagl Drugs cause?

3. Which medication causes “Shake and Bake”?

4. What symptoms are present in “Shake and Bake”?





Answers: 1. C & F 2. Renal Toxicity, Neurotoxicity, Hepatotoxicity 3. Amphotericin B 4. Fever, chills, headache, dysrhythmias, malaise, nausea, hypotension, anorexia, muscle and joint pain





MALARIA:



Word Search:
Word_search_for_pharm_002.jpg



1. What kind of mosquito is the cause of Malaria?
2. During which cycle are drugs to treat malaria effective?
3. Antimalarial agents that are effective during this stage are chloroquine and hydroxychloriquine.
4. and erythrocitic phases are part of the asexual life cycle of Malaria.
5 & 6. The symptoms fever,headache and vomiting occur between and ___ days,

7. Where do the parasites multiply in the human body?
8. The parasite that causes Malaria?
9. Using sulfonamides, tetracyclines and clindamycin increase what type of effects?





Answers: 1.ANOPHELINE, 2. ASEXUAL, 3. ERYTHROCYTIC, 4. EXOERYTHROCYTIC, 5. TEN, 6. FIFTEEN, 7. LIVER, 8. PLASMODIUM, 9. PROTOZOACIDAL





Antiprotozoal

What is a Protozoa?

Protozoans are single celled, free living, annimal like organisms ranging in size from .005mm to 5mm

What are some types of Protozoal infections?

  • Malria
  • Amebiasis
  • Giardiasis
  • Pneumocystosis
  • Toxoplasmosis
  • Trichomoniasis

Lets try to match the modes of transmission with the infection!!!!

very_absorbent_kitty_litter_854195.jpg 1) What is Caused by T. Gondi and transmitted by Cats through thier kitty litter?

2) What is Caused by P. Carinii and can be found in the lungs of healthy people?lungs.gif
mosqui1.jpg3) What is Caused by Plasmodium and can be transfered by infected mosquitoes?
4) What TWO infections are transfered by infected food and water? (One caused by G. Lamblia other by E. Histolytic) cartoon-food-picture_302200704.gif
CuteLoveKissHug4.jpg5) What is caused by T. Vaginalis and transmitted by sexual intercourse?

(Answers: 1- Toxoplasmosis 2- Pneumocystosis 3- Malaria 4- Giardiasis & Amebiasis 5- Trichomoniasis)

How do we kill them????? WITH ANTIPROTOZOAL AGENTS!!!
Agent
Infection
Side effects
Metronidazole(Flagyl)
  • amebiasis
  • giardiasis
  • toxoplasmosis
  • trichomoniasis
  • Metallic taste
  • Nausea
  • vomiting, diarrhea, abdominal cramps
  • Dark urine
Pentamidine (Pentam)
  • Pneumocystosis
  • Dizziness
  • confusion
Chloroquine
Hydroxychloroquine
Primaquine
  • Malaria
  • GI- Nausea,
  • vomiting, diarrhea, abdominal pain

Anthelmintic 

What are Helmintic infections?
An infection caused by a parasitic worm.


What are some types of Helmintic Infections?
· Hookworms
· Guinea Worms
· Tapeworms
· Roundworms
· Candiru Catfish

Lets try to match the WORMS with the infection!!!!


1) These worm’s eggs and larva usually live in soil and when they infect a humans they live in the in theroundworm.jpg intestines and can grow between 1 millimeter to 1 meter
2) These animals live in the small intestine and their  larvae penetrate humans producing a creeping eruptionhookworms_htm_txt_hookworm%20migrans.gif called cutaneous larva migrans.


tapeworm-closeup.jpg3) People can get this worm by eating raw or uncooked meat. This worm lives in the human intestine and can grow longer than 12 feet.

4) This worm lives and matures in the human body. It can grow up to 3 feet.guinea-worm.jpg
After a year, the worm emerges through a painful blister in the skin.

5) This parasite is in the family Trichomycteridae. All are native to the Amazon River. candiru[1][5].jpg

( 1- Roundworms 2- Hookworms 3- Tapeworms 4- Guinea Worms 5- Candiru Catfish)

How do we Kill them???? With Anthelmintics Agents!!!!!!
Agent
Infection
Side effects
Mebendazole (Vermox)
Parasitic worm infections
  • Diarrhea
  • Abdominal pain,
  • Metallic taste,
  • Unusual skin odor


THE END
tape.gif

Thank You!!!!!