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Herbals & Dietary Suppliments
Antibiotics - Part I - Chapter 38
Antibiotics - Part II - Chapter 39
Antiviral & Antitubercular Drugs
Antifungal, Antimalarial, Antiprotozoal, Anthelmintic Drugs
Anti-inflammatory & Antigout Drugs
Coagulation Modifying & Anemia Agents
Andrenergic & Andrenergic Blocking Drugs
Cholinergic & Cholinergic Blocking Drugs
Heart Failure Drugs
Antidysrhythmic & Antianginal Drugs
Antilipemic and Diuretic Agents
Acid Controlling & Bowel Disorder Drugs
Antiemetic & Antinausea Drugs
Analgesic Drugs & General and Local Anesthetics
Central Nervous System Stimulants and Depressants
*Biologic Response Modifying & Antirheumatoid Drugs
Pituitary, Thyroid & Antithyroid Drugs
Adrenal & Antidiabetic Agents
Antihystamines, Decongestants, Antitussives, Expectorants & Bronchodilators
Antiemetic & Antinausea Drugs
Antiemetic and Antinausea Medications
The unpleasant feeling that often precedes vomiting.
Forcible emptying of gastric, and occasionally, intestinal contents.
Antiemetic agents are used to relieve nausea and vomiting.
Antiemetic Drug Classes
-Scopolamine- Transdermal Patch
It it used to dry GI secretions and reduce smooth muscle spasms &
-for nausea, vomiting, and motion sickness
-also to dry secretions before surgery
Dizziness, drowsiness, blurred vision, dry mouth, rash
-Meclizine (Antivert, Bonine, Meni-D)These drugs block H1 receptors ins the same areas as anticholinergics, so they work in the same way
They are used for motion sickness, sedation, rhinitis, allergies, nausea, vomoting, and a nonproductive cough.
Dizziness, drowsiness, confusion, dry mouth
-Prochlorperazine (Compazine), Promethazine (Phenergan)These drugs block the Dopamine receptors on the CTZ; desensitizes CTZ to signals it receives from the body.
They also have anticholinergic effects.
They are primarily used for antipsychotic effects, they are also used for intractable hiccups, nausea, and vomiting.
Orthostatic hypotension, Akathisia, dystonia, and headache
-Metoclopramide (Reglan)Primary action: it stimulates peristalsis in GI tract which promotes gastric emptying. It also blocks Dopamine receptors on the CTZ which desensitizes CTZ to signals it receives.
Again, these drugs have anticholinergic effects.
They are used fro delayed gastric emptying, GERD, nausea, and vomiting.
Hypotension, sedation, headache, dry mouth, and Tartive Dyskinesia
-Ondansetron (Zofran)This class blocks serotonin receptors located in the GI tract, CTZ, and VC.It is used for nausea and vomiting associated with:
Post operative states
Hyperemesia in pregnancy
-Dronabinol (Marinol), Medical Marijuana
Mechanism of action: major psychoactive substance in marijuana, inhibitory effects on the reticulaer formation, thalamus, cerebral cortex.
The alteration in mood and perceptions of surroundings relieve nausea.
These drugs are used for nausea associated with cancer treatment and to facilitate weight gain in AIDS and anorexia
Many of these agents cause severe drowsiness so warn patients about driving or performing any hazardous tasks.
1). Which classification on antiemetic drugs causes a rash?
2). Which class is primarily used for antipsychotic effects but can be used for intractable hiccups?
3). Which drug is used to treat hyperemesis during pregnancy?
4). What is the primary action of Reglan?
5). Many antiemetic drugs cause ___?
6). Which drug class has the side effect of Ta
anticholinergics, 2). neuroleptics, 3). Zofran, 4). to stimulate peristalsis in GI tract, 5). severe drowsiness, 6). prokinetics
Lilley, L., Harrington, S., & Snyder, J. (2011).
Pharmacology and the nursing process.
St. Louis: Mosby
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